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Microsoft introduced a Safe Mode for Outlook starting with version 2002. You can use Safe Mode to start Outlook with all plugins disabled. To start in Safe Mode, simply hold down the Ctrl key while you start Outlook. Once in Safe Mode you can review/remove your plugins (on Outlook 2002 select About Microsoft Outlook from the Help menu and then click Disabled Items) (on Outlook 2007 select About Microsoft Outlook from the Help menu and select Disabled Items).

You can also start other Microsoft Office Applications in Safe Mode by holding the Ctrl key when launching them.